Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4709)
Related Products (4709)
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Dibutyl maleate
0 ImagesDibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice.
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FTC-146 precursor
0 ImagesFTC-146 precursor (Compound s6) is a drug intermediate that can be used to prepare σ-1 receptor positron emission tomography tracers ([¹⁸F]FTC-146).
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4-Fluororesorcinol
0 Images4‑Fluororesorcinol is a class of fluorinated resorcinol aromatic small molecules that participates in fluorescence-generating chemical reactions under alkaline conditions. 4‑Fluororesorcinol undergoes a fluorescence-generating reaction with dopamine in an alkaline aqueous solution system to produce an azacyclooctane derivative that emits blue fluorescence. 4‑Fluororesorcinol serves as a building block for fluorescent dyes.
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16α,17α-Epoxyprogesterone
0 Images16α,17α-Epoxyprogesterone is an important steroid, serving as an intermediate for many hormonal drugs such as Hydrocortisone (HY-N0583) and Megestrol (HY-B1834). 16α,17α-Epoxyprogesterone can further biotransform into another significant intermediate, 11α-hydroxy-16α,17α-epoxyprogesterone, to manufacture additional compounds.
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3-Acetylaniline
0 ImagesSynonyms: 3'-Aminoacetophenone3-Acetylaniline (3'-Aminoacetophenone) is a drug intermediate that can be used for the synthesis of quinoline derivatives.
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Fosmetpantotenate
0 ImagesSynonyms: RE-024Fosmetpantotenate is a phosphopantothenic acid (PPA) precursor designed to release PPA intracellularly, leading to restoration of CoA levels. Fosmetpantotenate is used to research pantothenate kinase-associated neurodegeneration.
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4-Bromo-3-fluorobenzaldehyde
0 Images4-Bromo-3-fluorobenzaldehyde is a drug intermediate that can be used for the synthesis of triaryl dimer antibacterial compounds.
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Diformylphloroglucinol
0 ImagesDiformylphloroglucinol is an acylphloroglucinol compound that can be used in the synthesis of Psiguadial B. Psiguadial B is a neuroprotective agent.
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m-PEG3400-NHS ester
0 ImagesSynonyms: mPEG3400-SC; mPEG3400-Succinimidyl esterm-PEG3400-NHS ester (mPEG3400-SC; mPEG3400-Succinimidyl ester) is a polyethylene glycol (PEG)-based biocompatibility-enhancing modifier. m‑PEG3400‑NHS ester enables PEGylation of molecules such as proteins, which reduces the immunogenicity and antigenicity of target molecules, decreases the tendency of protein aggregation, and protects proteins from hydrolysis. m-PEG3400-NHS ester can be used in drug delivery-related research.
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Daunomycinone
0 ImagesSynonyms: NSC-109351Daunomycinone (NSC-109351) is a metabolite of Daunomycin (HY-13062A) and anticancer intermediate. Daunomycinone binds to nucleic acids synergistically with metal ions. Daunomycinone can be used in the research of leukemia.
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1,3-Dibromo-5-methylbenzene
0 Images1,3-Dibromo-5-methylbenzene is an aromatic halide that can be used for the synthesis of other active compounds.
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Atorvastatin acetonide tert-butyl ester
0 ImagesAtorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
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5-Amino-2-picoline
0 Images5-Amino-2-picoline (5-Amino-2-methylpyridine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 5-Amino-2-picoline is also an important intermediate and can be used in the synthesis of other active compounds.
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(R,S,S,R,S)-Boc-Dap-NE
0 ImagesCat. No.: HY-78931ACAS No.: 2994330-72-0(R,S,S,R,S)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
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AFP464 dihydrochloride
0 ImagesCat. No.: HY-16031BPurity: 99.45%Synonyms: NSC710464 dihydrochlorideAFP464 (NSC710464) dihydrochloride is a prodrug of Aminoflavone (HY-132974) and an agonist of the aryl hydrocarbon receptor (AhR). AFP464 dihydrochloride downregulates the expression of α6-integrin (α6-integrin), inhibits breast tumor growth, reduces the population of tumor-initiating cells, disrupts mammosphere structure, induces the formation of mucin lake clusters, triggers DNA damage, and exerts antiproliferative activity. AFP464 dihydrochloride is rapidly converted to Aminoflavone by nonspecific esterases in plasma and cell culture media. AFP464 dihydrochloride is applicable to research related to breast cancer.
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3,5-Dimethoxybenzoic acid
0 Images3,5-Dimethoxybenzoic acid is an aromatic organic acid and antifungal agent. 3,5-Dimethoxybenzoic acid can also be used as an intermediate for anticancer agents. 3,5-Dimethoxybenzoic acid can be isolated from the leaves of Melia azedarach. 3,5-Dimethoxybenzoic acid exhibits antifungal activity against A. rabiei with an MIC of 0.125 mg/mL. 3,5-Dimethoxybenzoic acid has anti-wrinkle, anti-inflammatory, antioxidant, and skin regeneration effects.
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2,2-Diethoxyethanol
0 ImagesCat. No.: HY-W010354CAS No.: 621-63-62,2-Diethoxyethanol is a drug intermediate used in research related to Plasmodium falciparum infection.
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SN-38-CO-DMEDA TFA
0 ImagesSN-38-CO-DMEDA TFA is the intermediate product for synthesizing antibody-conjugated drug LND1035.
